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NATURAL KILLER CELL RECEPTORS

M. Tevfik Dorak

 

 

References

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112.      Tanamachi DM, Hanke T, Takizawa H, Jamieson AM, Raulet DR. Expression of natural killer receptor alleles at different Ly49 loci occurs independently and is regulated by major histocompatibility complex class I molecules. J Exp Med. 2001;193:307-315.

113.      Santourlidis S, Trompeter HI, Weinhold S, et al. Crucial role of DNA methylation in determination of clonally distributed killer cell Ig-like receptor expression patterns in NK cells. J Immunol. 2002;169:4253-4261.

114.      Trompeter HI, Gomez-Lozano N, Santourlidis S, et al. Three structurally and functionally divergent kinds of promoters regulate expression of clonally distributed killer cell Ig-like receptors (KIR), of KIR2DL4, and of KIR3DL3. J Immunol. 2005;174:4135-4143.

115.      Leung W, Iyengar R, Triplett B, et al. Comparison of killer Ig-like receptor genotyping and phenotyping for selection of allogeneic blood stem cell donors. J Immunol. 2005;174:6540-6545.

116.      Gardiner CM, Guethlein LA, Shilling HG, et al. Different NK cell surface phenotypes defined by the DX9 antibody are due to KIR3DL1 gene polymorphism. J Immunol. 2001;166:2992-3001.

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Further References:

- Yu J, Heller G, Chewning J, Kim S, Yokoyama WM, Hsu KC. Hierarchy of the human natural killer cell response is determined by class and quantity of inhibitory receptors for self-HLA-B and HLA-C ligands. J Immunol 2007;179(9):5977-89.

- Gourraud PA, Meenagh A, Anne Cambon-Thomsen A, Middleton D. Linkage disequilibrium organization of the human KIR superlocus. Immunogenetics 2010;62(11-12):729-40 (open access)

 

 

 

 

 

See also:

Shao W et al. MICA intron 1 sequences of conserved extended HLA haplotypes: implications for sequencing-based typing. Genes & Immunity 2004;5:371-4

MICA Polymorphisms in Conserved Extended Haplotypes - EFI 2006 Poster (see also Dorak, 2006)

 

Online Resources

KIR Nomenclature Report 2002: Immunogenetics (PDF); Eur J Immunogenet; Tissue Antigens; Hum Immunol

KIR Gene Cluster (Online NCBI Publication) by Carrington & Norman

KIR Sequence Database ( IPD )

KIR Sequence Database ( NCBI-dbLRC ) 

IMGT Tutorial on LRC and KIR 

HGNC KIR Gene Family Nomenclature

IHW NK Receptors and HLA Polymorphism

NCBI ENTREZ Gene for most current nomenclature on gene names and further details

Natural Killer Cell Recognition of Target Cells by David Hoskin

NK Cell Information (Collaborative NK Cell Encyclopedia) including NK Cell Journal Screen 

  

M.Tevfik Dorak, M.D., Ph.D.

25 July 2011

 

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